Infusion toxicology in preclinical studies are meant to asses the safety of therapeutic candidates intended for continuous administration in clinics. Slow infusions are possible through […] Read More
Category: Toxicity Studies
In vivo Mammalian Alkaline Comet Assay The test is used to detect the influence of potentially genotoxic substances in vivo under experimental conditions. Comet analysis […] Read More
Skin sensitization test in guinea pigs is a preferred method for the detection of the potential of a substance to cause allergic contact dermatitis. The […] Read More
The method is based on the assessment of the degree of eye damage after local exposure to a potential irritant. The occurrence of lesions of […] Read More
Acute dermal toxicity study is used to identify potential side effects following skin application of a test substance. The test is performed after a single […] Read More
Potential drug candidate development proceeds with the investigation of a variety of adverse effects including immune system failure. The service includes assessment of suppression or […] Read More
Chronic toxicity studies are performed for a period of 180 days to 1 year. During the study, the potential risks in relation to the anticipated […] Read More
Subacute/subchronic (repeated-dose) toxicity (MTD/NOAEL) Subacute systemic toxicity is defined as adverse effects occurring after multiple or continuous exposure between 24 h and 28 days. Subchronic systemic toxicity […] Read More
During the drug discovery process, preclinical/nonclinical toxicology studies are conducted to reveal a candidate molecule’s earliest potential toxic effects as it progresses from hit to […] Read More