New approach for solubility test is available at Bienta LTD with the Agilent 1260 Infinity that was installed at Bioanalytical Laboratory. The Agilent 1260 Infinity with Diode Array Detector equipped with OpenLab software is designed to provide high sensitivity (noise <±3µAU), and lowest peak dispersion for 2.1, 3 and 4.6 mm ID columns. Wide linear range (typically up to 2.5 AU) gives an advantage for reliable, simultaneous quantification of primary compounds, by-products and impurities. The Agilent 1260 Infinity has full spectral detection up to 80 Hz for compound identification by spectral libraries or verification of the separation quality with peak purity analysis for conventional and ultrafast liquid chromatography. Electronic temperature control provides maximum baseline stability and practical sensitivity under fluctuating ambient temperature and humidity conditions. Background interference is eliminated by reference wavelength. The optofluidic waveguides in the MaxLight cartridge cells eliminates almost any compromising refractive index and thermal effects, resulting in significantly less baseline drift for more reliable and precise peak integration which gives the Agilent 1260 Infinity highest baseline robustness.

This detector has great advantage if compare to MS/MS technique. It can detect spectra of non-ionizible compounds.