About Bienta

Bienta is a trademark for preclinical biology services of Enamine, the world’s largest supplier of drug-like molecules for drug discovery research. Bienta is operating as a Contract Research Organisation (CRO) providing biomolecular screening (HTS) services as well as comprehensive bioanalytical support of drug discovery projects, including in vitro ADMET (absorption, distribution, metabolism, excretion, toxicity) testing as well as pharmacokinetics (PK) and toxicity studies in animals.

Time- and Cost-Effective Screening

Rapid direct access to the vast Enamine’s off-the shelf compound collection (Screening Collection) and Enamine’s explored virtual chemical space for drug-like structures (REAL Database™),  in combination with the powerful in-house chemoinformatics and molecular modeling, enables an exceptionally efficient iterative screening, making it possible to step forward from in silico screening sets to the lead generation stage in weeks.

High Throughput Screening & ADME-Tox Services

HTS Lab at Bienta is a well-equipped screening facility with a broad range of robotic liquid handling and signal readout technology capabilities as well as the capacity to run both biochemical and cell-based assays in 384-well plate format. Bioanalytical Lab is established to provide all common in vitro ADMET tests as well as analytical support of pharmacokinetics and animal tox services.

Discover your molecules with us

News & Events

Metabolite identification

Knowing specific sites and pathways of metabolic transformations is useful for guiding synthetic optimization of lead compounds to overcome stability or toxicity issues commonly occurring in drug discovery. Over the last few years, Bienta’s ADME/mass-spectrometry team has accumulated substantial experience in running efficient and affordably priced Metabolite ID projects to help tackling the challenges of synthetic optimization for Enamine’s...

HitLocator Library for efficient HTS campaigns at Bienta

Since the end of 2015, we are offering HitLocator Library (HLL) consisting of 511,360 compounds for contractual HTS campaigns at Bienta. HLL is a carefully selected representation of the whole Enamine’s collection of more than 2,000,000 chemical compounds. HLL compounds were selected by applying chemical diversity and drug-likeness criteria and using extensive medchem filtering. HLL has an intelligently clustered...

New animal facility for in vivo studies launched at BIENTA

Bienta has just launched on-site laboratory for in vivo studies in rodents. This new animal facility allows us to continue expanding our services in preclinical toxicology and animal efficacy models, in addition to pharmacokinetics studies in mice and rats that Bienta was successfully offering for the last several years. Our immediate plans include setting up rodent efficacy models for...

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