A synergy of Enamine Chemistry and Bienta Biology: Medicinal Chemistry, Molecular Modeling, High-Throughput Screening, ADME-Tox. Weeks from in silico data set to hits and leads.
All laboratories at Bienta operate according to the standard international quality control practices. Bienta holds a permit from Ukrainian regulatory agencies to provide analytical support for clinical trial PK/bioequivalence studies in humans.
All of our personnel hold M.S. and Ph.D. degrees in Chemistry/Biology and many staff members have years of working experience in various research centers of the US and Europe.
Striving for excellence:
Outsource your research to the largest drug discovery CRO in Ukraine. We build our competitiveness on the integration with the established leader in screening compound libraries and custom chemistry and recruitment of the best local scientists in an emerging Eastern European economy.
Bienta is a trademark for preclinical biology services of Enamine, the world’s largest supplier of drug-like molecules for drug discovery research. Bienta is operating as a Contract Research Organisation (CRO) providing biomolecular screening (HTS) services as well as comprehensive bioanalytical support of drug discovery projects, including in vitro ADMET (absorption, distribution, metabolism, excretion, toxicity) testing as well as pharmacokinetics (PK) and toxicity studies in animals.
Time- and Cost-Effective Screening
Rapid direct access to the vast Enamine’s off-the shelf compound collection (Screening Collection) and Enamine’s explored virtual chemical space for drug-like structures (REAL Database™), in combination with the powerful in-house chemoinformatics and molecular modeling, enables an exceptionally efficient iterative screening, making it possible to step forward from in silico screening sets to the lead generation stage in weeks.
High Throughput Screening & ADME-Tox Services
HTS Lab at Bienta is a well-equipped screening facility with a broad range of robotic liquid handling and signal readout technology capabilities as well as the capacity to run both biochemical and cell-based assays in 384-well plate format. Bioanalytical Lab is established to provide all common in vitro ADMET tests as well as analytical support of pharmacokinetics and animal tox services.
Discover your molecules with us
News & Events
We will be paricipating in the 7th International Conference on Drug Discovery and Therapy (ICDDT), Sharjah, UAE, February 15th – 18th, 2016. Poster: Dubai CA 2016 Poster Discovery of Strecker-Type Aminonitriles as a New Class of Human Carbonic Anhydrase Inhibitors Using Differential Scanning Fluorimetry Roman Stavniichuk,a Sergey Zozulya,a Petro Borysko, a Daniela Vullo,b Claudiu T. Supuran,b and Mikhail Krasavinc a Enamine Ltd/Bienta,...
We will be participating in SLAS2016 Conference (San Diego, Jan 23-27, 2016), with a poster “Discovery of Novel SIRT1 Modulators Using Differential Scanning Fluorimetry” (№2125). Our poster presentation is scheduled on January 25, 1-3 р.m. SIRT1 SLAS2016 Poster Poster Abstract Discovery of Novel SIRT1 Modulators Using Differential Scanning Fluorimetry Sergey Zozulya, Ph.D. Enamine/Bienta 78 Chervonotkatska Str., Kyiv 02094, Ukraine Co-Authors: Roman...
Bienta has recently supported molecular modeling assessment project ran at Tokyo Institute of Technology, Japan. YES tyrosine kinase targeted library created by 10 competing in silico molecular modeling teams organized by Initiative for Parallel Bioinformatics ( IPAB) was successfully screened by Bienta to identify hits. The library consisting of 600 compounds was selected from Enamine’s Screening Compounds Collection of close to 2,000,000 compounds. Bienta enjoys unlimited and immediate...