Bienta has recently supported molecular modeling assessment project ran at Tokyo Institute of Technology, Japan. YES tyrosine kinase targeted library created by 10 competing in silico molecular modeling teams organized by Initiative for Parallel Bioinformatics ( IPAB) was successfully screened by Bienta to identify hits. The library consisting of 600 compounds was selected from Enamine’s Screening Compounds Collection of close to 2,000,000 compounds. Bienta enjoys unlimited and immediate access to the vast Enamine compound repository, allowing prompt and efficient high-throughput screening, hit verification “from powders” and hit expansion follow-ups.
absorption ADME assay biochemical bioequivalence channel chemoinformatics compound DELFIA development distribution docking Enamine excretion FLIPR FRET GPCR HTRF HTS in-silico ion kinase LANCE LC/MS library ligand membrane metabolism modeling molecular MS/MS permeability pharmacokinetics plate preclinical reader receptor screening software solubility targeted toxicity TR-FRET triple quadrupole virtual