YES Kinase Targeted Library Contest

Bienta has recently supported molecular modeling assessment project ran at Tokyo Institute of Technology, Japan. YES tyrosine kinase targeted library created by 10 competing in silico molecular modeling teams organized by Initiative for Parallel Bioinformatics ( IPAB) was successfully screened by Bienta to identify hits. The library consisting of 600 compounds was selected from Enamine’s  Screening Compounds Collection of close to 2,000,000 compounds.  Bienta enjoys unlimited and immediate access to the vast Enamine compound repository, allowing prompt and efficient high-throughput screening, hit verification “from powders” and hit expansion follow-ups.

The project report was published in NATURE Scientific Reports on 26 November 2015 and can be accessed here (open access).

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Bienta at MIPTEC 2014

Bienta will be participating at MIPTEC 2014 conference, September 23-25, Basel, Switzerland. Meet us there!
Our team member, Ihor Zahanich, will be presenting a poster “Pharmacological characterization of potent and selective Free Fatty Acid Receptor 1 (FFA1/GPR40) agonists for the treatment of type 2 diabetes”.  Author list: Ihor Zahanich, Olexandr Vasylchenko, Yuri Kheylik, Yulia Tokareva, Roman Moriev, Maxim Platonov, Vladimir Iurchenko, Sergey Zozulya.  Poster Session (Poster Area) to be held on Wednesday, 24 September 2014 between 17:00h and 18:00h.

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Differential Scanning Fluorimetry technology is now at Bienta

Introducing a new technology which is planned to be extensively used for screening projects at Bienta. Differential Scanning Fluorimetry (DSF, TSA) is a powerful biophysical method based on detecting the shifts in protein denaturation temperature upon ligand binding as reported by fluorescent dye interacting with protein core exposed by heat denaturation. DSF is a simple, label-free HTS technology applicable to most soluble proteins, irrespectively of their functions and activities. Now Bienta can provide on-site recombinant target protein production to support DSF-based screening projects.

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ASMC 2013

Feb 14, 2013  You are welcome to visit our booth and meet representatives of Enamine&Bienta Sales team at ASMC 2013 (5 – 8 May) (more…)

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Enamine launches preclinical biology laboratory

Jan 13, 2012 Enamine announces opening of contract biology laboratory at its main research site in Kyiv, Ukraine. Enamine’s BioLab will be providing ADMET (absorption, distribution, metabolism, excretion and toxicity) and biomolecular screening services to expand Enamine’s chemistry-driven CRO capabilities into the biological support of early phase drug discovery projects. (more…)

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