Bienta’s Laboratory Animal Research Centre was built in the end of 2018, in order to address rapidly growing demand in in vivo pharmacokinetic and toxicology studies in rodents. Our in vivo facilities currently occupy approximately 700 square meters (7000 square feet) of lab space, equipped and maintained according to current industrial quality standards. Animal housing conditions are constantly monitored according to AAALAC recommendations.
Our in-house core breeding unit is currently able to produce approximately 1200 animals per month. A stock of 10 various mice and rat strains were imported and maintained, in particular:
- two outbred (CD-1; NMRI (Han)) mice strains;
- four inbred (Balb/cAnN; C57BL/6N; C57BL/6J; C3H) mice strains;
- two immunodeficient (CD1-Foxnlnu/nu; CB17.Cg-PrkdcscidLystbj-J) mice strains;
- three rat strains (maintained separately): Wistar, SD (Sprague-Dawley) and SHR.
Other strains can be imported on customer’s demand, maintained and prepared for special experimental designs.
Our animals are usually housed by pairs or groups in suitable cages with small coverings to minimize stress and ensure most comfortable living conditions. Temperature, humidity and light/darkness cycle are constantly monitored and controlled. Bienta Animal Facility has adequate protection to maintain safe environment for the animals and to prevent contamination. Air ventilation barriers are designed to protect and secure Animal Facility staff as well as animals from any risk. Food and bedding is purchased from certified suppliers.
All our studies are designed and conducted under Bienta’s Institutional Animal Care and Use Committee (IACUC) review in accordance to the 3Rs rules (replacement, reduction, refinement). Our Animal Facility team is committed to comply with the International Guiding Principles for Biomedical Research Involving Animals.
Animal care at Bienta’s Laboratory Animal Research Centre is provided by trained personnel. Our Animal Facility professional team consists of biologists, geneticists, veterinarians and animal technicians. They support general maintenance of animals, breeding program, acclimatization and adaptation of new arrivals, hosting inspections, experimental performance and project coordination.